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Found 31 results
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Receptors, Aryl Hydrocarbon
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2018
G. R. Garcia
,
Bugel, S. M.
,
Truong, L.
,
Spagnoli, S.
, and
Tanguay, R. L.
,
“
AHR2 required for normal behavioral responses and proper development of the skeletal and reproductive systems in zebrafish.
”
,
PLoS One
, vol. 13, no. 3, p. e0193484, 2018.
2017
A. K. Ehrlich
,
Pennington, J. M.
,
Tilton, S.
,
Wang, X.
,
Marshall, N. B.
,
Rohlman, D.
,
Funatake, C.
,
Punj, S.
,
O'Donnell, E. F.
,
Yu, Z.
,
Kolluri, S.
, and
Kerkvliet, N. I.
,
“
AhR activation increases IL-2 production by alloreactive CD4 T cells initiating the differentiation of mucosal-homing Tim3 Lag3 Tr1 cells.
”
,
Eur J Immunol
, vol. 47, no. 11, pp. 1989-2001, 2017.
E. F. O'Donnell
,
Jang, H. Sang
,
Pearce, M. C.
,
Kerkvliet, N. I.
, and
Kolluri, S.
,
“
The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells.
”
,
Oncotarget
, vol. 8, no. 15, pp. 25211-25225, 2017.
G. R. Garcia
,
Goodale, B. C.
,
Wiley, M. W.
,
La Du, J. K.
,
Hendrix, D. A.
, and
Tanguay, R. L.
,
“
In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression.
”
,
Mol Pharmacol
, vol. 91, no. 6, pp. 609-619, 2017.
S. Kolluri
,
Jin, U. - H.
, and
Safe, S.
,
“
Role of the aryl hydrocarbon receptor in carcinogenesis and potential as an anti-cancer drug target.
”
,
Arch Toxicol
, vol. 91, no. 7, pp. 2497-2513, 2017.
2016
A. K. Ehrlich
,
Pennington, J. M.
,
Wang, X.
,
Rohlman, D.
,
Punj, S.
,
Löhr, C. V.
,
Newman, M. T.
,
Kolluri, S.
, and
Kerkvliet, N. I.
,
“
Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice.
”
,
J Immunol
, vol. 196, no. 1, pp. 264-73, 2016.
2015
B. C. Goodale
,
La Du, J.
,
Tilton, S. C.
,
Sullivan, C. M.
,
Bisson, W. H.
,
Waters, K. M.
, and
Tanguay, R. L.
,
“
Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.
”
,
Toxicol Sci
, vol. 147, no. 2, pp. 397-411, 2015.
2014
S. Punj
,
Kopparapu, P.
,
Jang, H. Sang
,
Phillips, J. Lynne
,
Pennington, J. M.
,
Rohlman, D.
,
O'Donnell, E. F.
,
Iversen, P. L.
,
Kolluri, S.
, and
Kerkvliet, N. I.
,
“
Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease.
”
,
PLoS One
, vol. 9, no. 2, p. e88726, 2014.
C. V. Gerlach
,
Das, S. R.
,
Volz, D. C.
,
Bisson, W. H.
,
Kolluri, S. K.
, and
Tanguay, R. L.
,
“
Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish.
”
,
Aquat Toxicol
, vol. 154, pp. 71-9, 2014.
2012
B. C. Goodale
,
La Du, J. K.
,
Bisson, W. H.
,
Janszen, D. B.
,
Waters, K. M.
, and
Tanguay, R. L.
,
“
AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish.
”
,
PLoS One
, vol. 7, no. 1, p. e29346, 2012.
E. F. O'Donnell
,
Kopparapu, P. Rao
,
Koch, D. C.
,
Jang, H. Sang
,
Phillips, J. Lynne
,
Tanguay, R. L.
,
Kerkvliet, N. I.
, and
Kolluri, S. Kumar
,
“
The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.
”
,
PLoS One
, vol. 7, no. 7, p. e40926, 2012.
2010
E. F. O'Donnell
,
Saili, K. S.
,
Koch, D. C.
,
Kopparapu, P. R.
,
Farrer, D.
,
Bisson, W. H.
,
Mathew, L. K.
,
Sengupta, S.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
, and
Kolluri, S. Kumar
,
“
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor.
”
,
PLoS One
, vol. 5, no. 10, 2010.
2009
L. K. Mathew
,
Simonich, M. T.
, and
Tanguay, R. L.
,
“
AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration.
”
,
Biochem Pharmacol
, vol. 77, no. 4, pp. 498-507, 2009.
W. H. Bisson
,
Koch, D. C.
,
O'Donnell, E. F.
,
Khalil, S. M.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Abagyan, R.
, and
Kolluri, S. Kumar
,
“
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.
”
,
J Med Chem
, vol. 52, no. 18, pp. 5635-41, 2009.
2008
L. K. Mathew
,
Sengupta, S. S.
,
LaDu, J.
,
Andreasen, E. A.
, and
Tanguay, R. L.
,
“
Crosstalk between AHR and Wnt signaling through R-Spondin1 impairs tissue regeneration in zebrafish.
”
,
FASEB J
, vol. 22, no. 8, pp. 3087-96, 2008.
B. R. Evans
,
Karchner, S. I.
,
Allan, L. L.
,
Pollenz, R. S.
,
Tanguay, R. L.
,
Jenny, M. J.
,
Sherr, D. H.
, and
Hahn, M. E.
,
“
Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator.
”
,
Mol Pharmacol
, vol. 73, no. 2, pp. 387-98, 2008.
2007
E. A. Andreasen
,
Mathew, L. K.
,
Löhr, C. V.
,
Hasson, R.
, and
Tanguay, R. L.
,
“
Aryl hydrocarbon receptor activation impairs extracellular matrix remodeling during zebra fish fin regeneration.
”
,
Toxicol Sci
, vol. 95, no. 1, pp. 215-26, 2007.
2006
L. K. Mathew
,
Andreasen, E. A.
, and
Tanguay, R. L.
,
“
Aryl hydrocarbon receptor activation inhibits regenerative growth.
”
,
Mol Pharmacol
, vol. 69, no. 1, pp. 257-65, 2006.
A. L. Prasch
,
Tanguay, R. L.
,
Mehta, V.
,
Heideman, W.
, and
Peterson, R. E.
,
“
Identification of zebrafish ARNT1 homologs: 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in the developing zebrafish requires ARNT1.
”
,
Mol Pharmacol
, vol. 69, no. 3, pp. 776-87, 2006.
2005
C. J. Funatake
,
Marshall, N. B.
,
Steppan, L. B.
,
Mourich, D. V.
, and
Kerkvliet, N. I.
,
“
Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells.
”
,
J Immunol
, vol. 175, no. 7, pp. 4184-8, 2005.
C. Weiss
,
Faust, D.
,
Dürk, H.
,
Kolluri, S.
,
Pelzer, A.
,
Schneider, S.
,
Dietrich, C.
,
Oesch, F.
, and
Göttlicher, M.
,
“
TCDD induces c-jun expression via a novel Ah (dioxin) receptor-mediated p38-MAPK-dependent pathway.
”
,
Oncogene
, vol. 24, no. 31, pp. 4975-83, 2005.
2004
J. M. Zodrow
,
Stegeman, J. J.
, and
Tanguay, R. L.
,
“
Histological analysis of acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in zebrafish.
”
,
Aquat Toxicol
, vol. 66, no. 1, pp. 25-38, 2004.
2003
J. M. Zodrow
and
Tanguay, R. L.
,
“
2,3,7,8-tetrachlorodibenzo-p-dioxin inhibits zebrafish caudal fin regeneration.
”
,
Toxicol Sci
, vol. 76, no. 1, pp. 151-61, 2003.
2002
E. A. Andreasen
,
Tanguay, R. L.
,
Peterson, R. E.
, and
Heideman, W.
,
“
Identification of a critical amino acid in the aryl hydrocarbon receptor.
”
,
J Biol Chem
, vol. 277, no. 15, pp. 13210-8, 2002.
E. A. Andreasen
,
Spitsbergen, J. M.
,
Tanguay, R. L.
,
Stegeman, J. J.
,
Heideman, W.
, and
Peterson, R. E.
,
“
Tissue-specific expression of AHR2, ARNT2, and CYP1A in zebrafish embryos and larvae: effects of developmental stage and 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure.
”
,
Toxicol Sci
, vol. 68, no. 2, pp. 403-19, 2002.
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